To test the wire for leakage, start the engine. Place your right hand on the right shock tower. Dip your left hand into a pail of water, then slide it along the entire length of the wire. You will quickly find the point of leakage.

A less exciting way is to pour some of the water from the pail into a trigger sprayer bottle. At night, away from lights, with the engine running, spritz down the ignition wires. You should see any leaking wires. I'd also suggest that you pull the plug for # 1 and see that it's actually gapped at 45. Remove the distributor cap and look for tracking or cracks on the inside from the area of the # 1 terminal. Don't use fancy-schmancy double-tipped, platinum or any other higher dollar plugs. Generally the Fiero doesn't like them. R42CTS was the standard plug for the 2.8. I think they were either Champion, Autolite or AC Delco. I believe the emissions decal on the deck lid will tell you.
If these prove not to be the cause, try swapping the wire with a spare.